Linking Brain Connectivity to Borderline Personality Disorder

Symptoms on the borderline personality spectrum (BPS) often begin in childhood and adolescence, yet the underlying developmental neurobiology of these debilitating symptoms remains sparsely explored. Here, we seek to describe functional network abnormalities linked to the BPS in both young adults and children.

Project Lead(s)

Arielle Keller, taken over from Max Bertolero

Faculty Lead(s)

Satterthwaite

Analytic Replicator

TBD

Collaborators

TBD

Project Start Date

late 2020

Current Project Status

10) Data analysis and documentation

Dataset

HCP-YA, HCP-D, NKI, PNC

Github repo

https://github.com/PennLINC/borderline/

Path to data on filesystem

/cbica/home/bertolem/bpd

Slack Channel

$bpd_fmri

Trello board

https://trello.com/b/8hIMxFcC/bpd

Box Folder

https://upenn.box.com/s/olnuor4clzw2k5idtwtzre686z87imdd

Current work products

SOBP Poster

Code documentation

All of the code is in bpd.py

The data can be regenerated by calling these functions:

submit_make_data(‘hcpya’) submit_make_data(‘hcpd-dcan’) submit_predict(‘hcpya’,1,1) submit_predict(‘hcpd-dcan’,1,1) submit_dev_predict()

The figures can be regenerated by calling these functions:

analyze_predict(‘hcpya’,1,1) analyze_predict(‘hcpd-dcan’,1,1) apply_hcpya_2_dev() analyze_developmental()