About the dataset

Primary description: Type 2 diabetes and cardiovascular outcomes

The Action to Control Cardiovascular Risk in Diabetes (ACCORD) is a clinical trial evaluated intensive glycemic control on a cohort of participants with type 2 diabetes. The Memory in Diabetes (MIND) sub-study further evaluated cognitive and structural brain outcomes in a subset of participants from the two randomized groups of ACCORD study.

Study Action to Control Cardiovascular Risk in Diabetes
Study Website ACCORD
Data Descriptor Paper https://pmc.ncbi.nlm.nih.gov/articles/PMC5633725/
https://pubmed.ncbi.nlm.nih.gov/21958949/
DUA https://biolincc.nhlbi.nih.gov/studies/accord/
Country/Region USA
Disease Tag diabetes
Age (mean ± SD)
(Baseline)
62.9 ± 5.8
Age Range
(Baseline)
54.7-79.3
% Female 44.6
CUBIC Project /cbica/projects/accord
PI for Access Approval Christos Davatzikos
N Subjects 629
N MR Sessions 1414
Diagnoses
Hypertension
Value V1 V2 V3
Stage2 496 100
Normal 64 270
Stage1 45 111
nan 19 260
Diabetes
Value V1 V2 V3
Diabetic 605 481
nan 19 260
DLMUSE (v1.0.7)
(1411/1414 complete)
/cbica/projects/accord/Pipelines/ACCORD_DLMUSE_2025/Results/DLMUSE_Volumes.csv
RAVENS (DRAMMS-1.4.1)
(1408/1414 complete)
/cbica/projects/accord/Pipelines/ACCORD_3.5D_2020/Protocols/RAVENS
DLWMLS (v0.1.0)
(1308/1389 complete)
/cbica/projects/accord/Pipelines/ACCORD_DLWMLS_2025/Results/ACCORD_DLWMLS_DLMUSE_Segmented_Volumes.csv
Non-Imaging Data
/cbica/projects/ISTAGING/Pipelines/ClinicalDataConsolidation_201911/Data/External_Data/ACCORD

Raw data downloaded from source.

/cbica/projects/ISTAGING/Pipelines/ClinicalDataConsolidation_201911/dictionaries/ACCORD/ACCORD Data Dictionary.pdf

Data dictionary of raw data downloaded from source.

/cbica/projects/ISTAGING/Pipelines/ISTAGING_Data_Consolidation_2020/v2.0/istaging.csv

Data consolidated and harmonized in 2020.

This study: subset with df[df.Study == 'ACCORD']

README: /cbica/projects/ISTAGING/Pipelines/ISTAGING_Data_Consolidation_2020/v2.0/README.md

Release Notes: /cbica/projects/ISTAGING/Pipelines/ISTAGING_Data_Consolidation_2020/v2.0/Release_Notes.md

Coming Soon

Data consolidated and harmonized in 2026.

This study: subset with df[df.Study == 'ACCORD']

README: Coming Soon

Release Notes: Coming Soon


Funding
National Institute of Aging and the National Heart, Lung, and Blood Institute of the National Institutes of Health