Manchester Brain Imaging Study
About the dataset
Primary description: University of Manchester cohorts
The University of Manchester cohort combines three smaller cohorts and includes an eight-week trial of the SSRI citalopram and included MRI scans at baseline for both those with major depressive disorder and healthy controls. For more information, see https://doi.org/10.1186/s12888-022-04509-7.
The study is part of the COORDINATE-MDD consortium. For more information, see: https://doi.org/10.1038/s44220-023-00187-w.
The study is part of the COORDINATE-MDD consortium. For more information, see: https://doi.org/10.1038/s44220-023-00187-w.
| Study | Manchester Brain Imaging Study | |
|---|---|---|
| Data Descriptor Paper | https://doi.org/10.1176/appi.ajp.2012.11121774 | |
| DUA | Please contact Dr. Christos Davatzikos to obtain the DUA for the derived data and request an introduction to the study PI to obtain the DUA for the raw data. | |
| Country/Region | UK | |
| Disease Tag | depression | |
| Age (mean ± SD)
(Baseline) |
35.1 ± 8.9 | |
| Age Range
(Baseline) |
20-56 | |
| % Female | 68.6 | |
| CUBIC Project | /cbica/projects/MultisiteMD |
|
| PI for CUBIC Access Approval | Christos Davatzikos | |
| N Subjects | 70 | |
| N MR Sessions | 121 | |
|
DLMUSE
(121/121 complete) |
/cbica/projects/MultisiteMD/Pipelines/MultisiteMD_DLMUSE_2025/Manchester-Remedi/Results/Manchester-Remedi_DLMUSE_Volumes.csv
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RAVENS
(DRAMMS-1.4.1)
(70/70 complete) |
/cbica/projects/MultisiteMD/Pipelines/CoordinateMD_3.5D_2020/Protocols/RAVENS/Manchester-Remedi
|
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fMRIPrep
(23.1.3)
(69/121 complete) |
/cbica/projects/MultisiteMD/CoordinateMD_Studies/Manchester-Remedi/Pipelines/Manchester-Remedi_fMRI_2024/Protocols/
/opt/conda/envs/fmriprep/bin/fmriprep \
/cbica/projects/MultisiteMD/CoordinateMD_Studies/Manchester-Remedi/Pipelines/Manchester-Remedi_fMRI_2024/Data/ \
/cbica/projects/MultisiteMD/CoordinateMD_Studies/Manchester-Remedi/Pipelines/Manchester-Remedi_fMRI_2024/Protocols/ \
participant \
--participant_label 0001 \
--skip-bids-validation \
--fs-license-file /cbica/projects/MultisiteMD/CoordinateMD_Studies/Manchester-Remedi/Pipelines/Manchester-Remedi_fMRI_2024/license.txt \
--fs-no-reconall \
--use-syn-sdc warn \
--output-spaces MNI152NLin2009cAsym:res-2 \
--debug all
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XCP-D
(0.7.1rc6)
(69/121 complete) |
/cbica/projects/MultisiteMD/CoordinateMD_Studies/Manchester-Remedi/Pipelines/Manchester-Remedi_fMRI_2024/Protocols/XCP/
/usr/local/miniconda/bin/xcp_d \
/cbica/projects/MultisiteMD/CoordinateMD_Studies/Manchester-Remedi/Pipelines/Manchester-Remedi_fMRI_2024/Protocols/ \
/cbica/projects/MultisiteMD/CoordinateMD_Studies/Manchester-Remedi/Pipelines/Manchester-Remedi_fMRI_2024/Protocols/XCP/ \
participant \
--participant_label 0001 \
--input-type fmriprep \
-p 36P \
--work-dir /cbica/projects/MultisiteMD/CoordinateMD_Studies/Manchester-Remedi/Pipelines/Manchester-Remedi_fMRI_2024/Protocols/ \
--motion-filter-type lp \
--band-stop-min 6 \
--motion-filter-order 4 \
--despike \
--fd-thresh 0 \
--lower-bpf 0.01 \
--upper-bpf 0.08 \
--bpf-order 2 \
--head-radius auto \
--dummy-scans auto \
--min-coverage 0.5 \
--smoothing 0 \
--fs-license-file /cbica/projects/MultisiteMD/CoordinateMD_Studies/Manchester-Remedi/Pipelines/Manchester-Remedi_fMRI_2024/license.txt
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| Non-Imaging Data |
Contact Mathilde Antoniades to request access to the non-imaging data. /cbica/home/harmang/for_others/final_combined_istaging_withMUSE.csv
Data consolidated and harmonized in 2026. This study: subset with |
Funding
R01 MH123550/MH/NIMH NIH HHS/United States
R01 MH112070/MH/NIMH NIH HHS/United States
R01 MH080880/MH/NIMH NIH HHS/United States
R01 MH101472/MH/NIMH NIH HHS/United States
G0902304/MRC_/Medical Research Council/United Kingdom