University of Pennsylvania Study

About the dataset

Primary description: Memory and Alzheimers research

The PENN dataset was collected at the University of Pennsylvania’s Memory Center, including participants with memory complaints and early stages of cognitive decline. Data collection is compatible with the standard National Alzheimer’s Coordinating Center’s uniform data set.

Study University of Pennsylvania (PENN) Study

Study Website PENN

Data Descriptor Paper https://doi.org/10.1136/jnnp-2012-302548

DUA Please contact Dr. Christos Davatzikos to obtain the DUA for the derived data and request an introduction to the study PI to obtain the DUA for the raw data.

Country/Region USA

Disease Tag alzheimers

Age (mean ± SD) 72.9 ± 9.3

Age Range 23-92.22

% Female 56.6

CUBIC Project /cbica/projects/chrisclark

PI for CUBIC Access Approval Christos Davatzikos

PENN-ADC

Diagnoses

Value	V01	V02
CN	54	1
MCI	20	2
AD	15	1
nan	11	25
early MCI	3
dementia	1
Vascular Dementia	1

N Subjects 405

N MR Sessions 405

DLMUSE (v1.0.7)
(405/405 complete)

/cbica/projects/chrisclark/ADC/Pipelines/ABC_DLMUSE_2025/Results/DLMUSE_Volumes.csv

RAVENS (DRAMMS-1.4.1)
(402/402 complete)

/cbica/projects/chrisclark/ADC/Pipelines/ABC_3.5D_2020/Protocols/RAVENS

DLWMLS (v0.1.0)
(369/369 complete)

/cbica/projects/chrisclark/ADC/Pipelines/ABC_DLWMLS_2025/Results/ABC_DLWMLS_DLMUSE_Segmented_Volumes.csv

Non-Imaging Data

/cbica/projects/ISTAGING/Pipelines/ClinicalDataConsolidation_201911/Data/External_Data/PennADC

Raw data downloaded from source.

/cbica/projects/ISTAGING/Pipelines/ISTAGING_Data_Consolidation_2020/v2.0/istaging.csv

Data consolidated and harmonized in 2020.

This study: subset with df[df.Study == 'PENN-ADC']

README: /cbica/projects/ISTAGING/Pipelines/ISTAGING_Data_Consolidation_2020/v2.0/README.md

Release Notes: /cbica/projects/ISTAGING/Pipelines/ISTAGING_Data_Consolidation_2020/v2.0/Release_Notes.md

/cbica/home/harmang/for_others/final_combined_istaging_withMUSE.csv

Data consolidated and harmonized in 2026.

This study: subset with df[df.Study == 'PENN-ADC']

PENN-PMC

Diagnoses

Value	V01	V02	V03	V04	V05	V06
AD	315	25	9	4	3	1
MCI	231	31	8	2
nan	161	21	5	3	1
CN	55	20	5	4	2	1
early MCI	36
dementia	32	3
Vascular Dementia	25
other	15	2	1
Hydrocephalus	14	3	1
FTD	13	1
PD	12
Lewy Body Dementia	9	1	1
PCA	4
TBI	4

N Subjects 1151

N MR Sessions 1151

DLMUSE (v1.0.7)
(1151/1151 complete)

/cbica/projects/chrisclark/ADC/Pipelines/PMC_DLMUSE_2025/Results/DLMUSE_Volumes.csv

RAVENS (DRAMMS-1.4.1)
(1151/1151 complete)

/cbica/projects/chrisclark/ADC/Pipelines/PMC_3.5D_2020/Protocols/RAVENS

DLWMLS (v0.1.0)
(1048/PENN-ADC=3741048 complete)

/cbica/projects/chrisclark/ADC/Pipelines/PMC_DLWMLS_2025/Results/PMC_DLWMLS_DLMUSE_Segmented_Volumes.csv