About the dataset

This is the neuroimaging dataset for the Philadelphia Neurodevelopmental Cohort (PNC). PNC is a large-scale study of child development that combines neuroimaging, diverse clinical and cognitive phenotypes, and genomics. Data from this rich resource is now publicly available through the Database of Genotypes and Phenotypes (dbGaP). The Philadelphia Neurodevelopmental Cohort (PNC) is a research initiative funded by NIMH through the American Reinvestment and Recovery Act of 2009 (ARRA). The initiative focuses on characterizing brain and behavior interaction with genetics. This is a collaborative research effort between the Brain Behavior Laboratory at the University of Pennsylvania and the Center for Applied Genomics at the Children’s Hospital of Philadelphia, led by Raquel E. Gur, MD, PhD at the University of Pennsylvania and Hakon Hakonarson, MD, PhD at the Children’s Hospital of Philadelphia (CHOP).

This version of the dataset was curated at the University of Pennsylvania by the Lifespan Informatics and Neuroimaging Center (PennLINC) as part of the Reproducible Brain Chart (RBC) Initiative.

PI Raquel E. Gur
Hakon Hakonarson
Institution University of Pennsylvania
Study Website Philadelphia Neurodevelopmental Cohort
Data Descriptor Paper https://doi.org/10.1016/j.neuroimage.2013.07.064
CUBIC Project pennlinc_rbc
DUA None
License CC BY-NC-SA
Sample Size 1601
Number of Sessions 1601
CuBIDS v1.0.5
BABS v0.0.9.dev30+gfa8f813
Demographics View available demographics data
Average Age (y) 14.9
% Female 52
% Right Handed 84
T1w QC View T1w QC , View T1w QC Variables , View RBC Paper for T1w QC Method
BIDS Datalad Dataset
ria+file:///cbica/projects/pennlinc_rbc/datasets/LINC_PNC/BIDS
sMRIprep v25-0-0
(1599/1601 complete)
ria+file:///cbica/projects/pennlinc_rbc/datasets/LINC_PNC/derivatives/fmriprep_anat-25-0-0-babs/output_ria#~data
/cbica/projects/pennlinc_rbc/datasets/LINC_PNC/derivatives/FMRIPREP_ANAT-25-0-0_zipped
FreeSurfer-Post v0-1-2
(1599/1601 complete)
ria+file:///cbica/projects/pennlinc_rbc/datasets/LINC_PNC/derivatives/freesurferpost-0-1-2-babs/output_ria#~data
/cbica/projects/pennlinc_rbc/datasets/LINC_PNC/derivatives/FREESURFERPOST-0-1-2_zipped
fMRIprep v25-0-0
(1561/1561 complete)
ria+file:///cbica/projects/pennlinc_rbc/datasets/LINC_PNC/derivatives/fmriprep_func-25-0-0-babs/output_ria#~data
/cbica/projects/pennlinc_rbc/datasets/LINC_PNC/derivatives/FMRIPREP_FUNC-25-0-0_zipped
XCP-D v0-10-6
(1561/1561 complete)
ria+file:///cbica/projects/pennlinc_rbc/datasets/LINC_PNC/derivatives/xcpd-0-10-6-babs/output_ria#~data
/cbica/projects/pennlinc_rbc/datasets/LINC_PNC/derivatives/XCPD-0-10-6_zipped
/cbica/projects/pennlinc_rbc/datasets/LINC_PNC/derivatives/QC/func/xcpd_qc/all_xcpd_qc_metrics.tsv
QSIPrep v1-0-0rc1
(1406/1409 complete)
ria+file:///cbica/projects/pennlinc_rbc/datasets/LINC_PNC/derivatives/qsiprep-1-0-0rc1-babs/output_ria#~data
/cbica/projects/pennlinc_rbc/datasets/LINC_PNC/derivatives/QSIPREP-1-0-0rc1_zipped
QSIRecon (Bundle Stats) v1-1-0
(1406/1409 complete)
ria+file:///cbica/projects/pennlinc_rbc/datasets/LINC_PNC/derivatives/qsirecon-1-1-0-babs/output_ria#~data
/cbica/projects/pennlinc_rbc/datasets/LINC_PNC/derivatives/QSIRECON-1-1-0_BUNDLE-STATS_zipped
QSIRecon (Whole Brain) v1-1-0
Coming Soon
Coming Soon


Funding
RC2MH089983, RC2MH089924, NIMH R01MH120482.

Citations

  1. Satterthwaite TD, Elliott MA, Ruparel K, Loughead J, Prabhakaran K, Calkins ME, Hopson R, Jackson C, Keefe J, Riley M, Mentch FD, Sleiman P, Verma R, Davatzikos C, Hakonarson H, Gur RC, Gur RE. Neuroimaging of the Philadelphia neurodevelopmental cohort. Neuroimage. 2014 Feb 1;86:544-53. doi: 10.1016/j.neuroimage.2013.07.064. Epub 2013 Aug 3. PMID: 23921101; PMCID: PMC3947233.

  2. Satterthwaite TD, Connolly JJ, Ruparel K, Calkins ME, Jackson C, Elliott MA, Roalf DR, Hopson R, Prabhakaran K, Behr M, Qiu H, Mentch FD, Chiavacci R, Sleiman PMA, Gur RC, Hakonarson H, Gur RE. The Philadelphia Neurodevelopmental Cohort: A publicly available resource for the study of normal and abnormal brain development in youth. NeuroImage. 2016 Jan 1 ;124:1115–9.