About the dataset

Primary description: Medical center cohorts

The study is part of the PHENOM consortium. For more information, see: https://doi.org/10.1038/s41380-023-02069-0 and https://doi.org/10.1093/brain/awaa025. The PHENOM (Psychosis Heterogeneity Evaluated Via Dimensional Neuroimaging) consortium is an international consortium pooling MRI and clinical data across several institutions world-wide. The focus on the consortium is to study the use of machine learning and MRI as a means for deriving personalized imaging signatures of schizophrenia, and of predicting future clinical progression. An associated goal is to use state of the art weakly supervised machine learning methods to dissect neuroanatomical heterogeneity in psychosis. In addition to offering healthy control subjects at younger ages, this consortium helps establish imaging signatures of psychosis into NiChart.
Study University Medical Center Utrecht Brain Imaging Study
Data Descriptor Paper https://doi.org/10.1038/s41380-023-02069-0
DUA Please contact Dr. Christos Davatzikos to obtain the DUA for the derived data and request an introduction to the study PI to obtain the DUA for the raw data.
Country/Region Netherlands
Disease Tag psychosis
Age (mean ± SD) 31.3 ± 11.3
Age Range 16-67.49
% Female 34.4
CUBIC Project /cbica/projects/PsychAnalysis
PI for CUBIC Access Approval Christos Davatzikos
UMC_Utrecht_T13Dsch
Diagnoses
Stroke
Value V01
0.0 238
nan 82
1.0 3
Psychosis
Value V01
0.0 133
1.0 108
nan 82
Schizophrenia
Value V01
0.0 229
nan 82
1.0 12
Depression
Value V01
0.0 238
nan 82
1.0 3
N Subjects 530
N MR Sessions 530
DLMUSE (v1.0.7)
(530/530 complete)
/cbica/projects/PsychAnalysis/Pipelines/PHENOM_DLMUSE_2025/UMC_Utrecht_T13Dsch/Results/UMC_Utrecht_T13Dsch_DLMUSE_Volumes.csv
Non-Imaging Data

Contact Mathilde Antoniades to request access to the non-imaging data.

/cbica/home/harmang/for_others/final_combined_istaging_withMUSE.csv

Data consolidated and harmonized in 2026.

This study: subset with df[df.Study == 'UMC_Utrecht_T13Dsch']
UMC_Utrecht_ffe
Diagnoses
N Subjects 302
N MR Sessions 302
DLMUSE (v1.0.7)
(302/302 complete)
/cbica/projects/PsychAnalysis/Pipelines/PHENOM_DLMUSE_2025/UMC_Utrecht_ffe/Results/UMC_Utrecht_ffe_DLMUSE_Volumes.csv
Non-Imaging Data

Contact Mathilde Antoniades to request access to the non-imaging data.

/cbica/home/harmang/for_others/final_combined_istaging_withMUSE.csv

Data consolidated and harmonized in 2026.

This study: subset with df[df.Study == 'UMC_Utrecht_ffe']


Funding
The PHENOM study is funded by NIA grant R01MH112070 and by the PRONIA project as funded by the European Union 7th Framework Program grant 602152. Other supporting funds are 5U01AG068057, 1U24AG074855, R01MH119219 and S10OD023495.